My personal favourite is still the example of Japanese researchers who were studying the origins of life - considered an esoteric, pure science field - and discovered an efficient way of producing fertiliser!
Another good story is told in the book Mauve where a chemist studying malaria discovered an artificial colour, and to the disgust of his peers (who had also produced colours as by-products) went commercial. Almost ironically, years later artificial colourants in cellular biology lead to better knwoledge of malaria :)
Can anyone else think of examples where science has led to unexpected turns?
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